Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024899
Disease: Mastocytosis
Mastocytosis
0.020 Biomarker disease BEFREE Imatinib has been reported to be an effective treatment for FIP1L1-PDGFRalpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans. 16485879 2006
CUI: C0024899
Disease: Mastocytosis
Mastocytosis
0.020 Biomarker disease BEFREE In vitro and in vivo studies confirmed that FIP1L1-PDGFRalpha is a therapeutic target of imatinib, forming a rational basis for the treatment of FIP1L1-PDGFRA positive chronic eosinophilic leukemia and mastocytosis with imatinib. 14676627 2004