CLTCL1, clathrin heavy chain like 1, 8218

N. diseases: 9; N. variants: 62
Disease: Pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030193
Disease: Pain
Pain 		0.030 Biomarker phenotype BEFREE Here, we present evidence that CHC22 has a non-redundant role in an early stage of neural precursor differentiation, providing a potential explanation of why CHC22 deficient patients are unable to feel touch or pain. 29402896 2018
CUI: C0030193
Disease: Pain
Pain 		0.030 Biomarker phenotype BEFREE These results reveal an essential and non-redundant role for CHC22 in neural crest development and in the genesis of pain and touch sensing neurons. 26068709 2015
CUI: C0030193
Disease: Pain
Pain 		0.030 Biomarker phenotype BEFREE The discovery of new genes essential for sensing pain (SCN11A, PRDM12, and CLTCL1) has provided unexpected insights into the biological mechanisms that drive distinct stages of nociception. 26549885 2015