EPX, eosinophil peroxidase, 8288

N. diseases: 44; N. variants: 5
Disease: Diphtheria ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0012546
Disease: Diphtheria
Diphtheria 		0.020 Biomarker disease BEFREE We developed a novel conditional eosinophil-deficient strain of mice (iPHIL) through a gene knock-in strategy inserting the human diphtheria toxin (DT) receptor (DTR) into the endogenous eosinophil peroxidase genomic locus. 24266710 2014
CUI: C0012546
Disease: Diphtheria
Diphtheria 		0.020 GeneticVariation disease BEFREE We generated novel basophil- and eosinophil-depletion mouse models by introducing the human diphtheria toxin (DT) receptor gene under the control of the mouse CD203c and the eosinophil peroxidase promoter, respectively, to study the critical roles of these cells in the immunological response. 23577180 2013