EPX, eosinophil peroxidase, 8288

N. diseases: 44; N. variants: 5
Disease: Eosinophilic esophagitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0341106
Disease: Eosinophilic esophagitis
Eosinophilic esophagitis 		0.020 Biomarker disease BEFREE Esophageal biopsies from eosinophilic esophagitis subjects demonstrated marked eosinophil peroxidase deposition (median score 46 vs. 0, P < 0.0001). 29228243 2018
CUI: C0341106
Disease: Eosinophilic esophagitis
Eosinophilic esophagitis 		0.020 Biomarker disease BEFREE We have (1) established a validated, parent proxy-reported measure for pediatric EoE, the PEESS v2.0; (2) verified that the parent proxy effectively captures symptoms; (3) determined that the dysphagia domain most closely aligns with symptoms and tissue-based molecular biomarkers; (4) established that symptoms correlate with EPX staining; and (5) observed association between mast cells and dysphagia. 26051952 2015