BAP1, BRCA1 associated protein 1, 8314

N. diseases: 299; N. variants: 72
Disease: Carcinoma of lung ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 GeneticVariation disease BEFREE Mutations in PBRM-1 and BAP-1 genes, and the expression of S100P have been related to survival in ICC. miR-31 seems also to play important regulatory functions in ICC and it directly regulates BAP-1 expression in lung cancer. 30377796 2019
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 GeneticVariation disease BEFREE Our study indicate that common germline genetic variants of <i>BAP1</i> play a role in mediating the risk of developing renal cell carcinoma and lung cancer. 29088836 2017
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 Biomarker disease BEFREE BAP1 suppresses lung cancer progression and is inhibited by miR-31. 26885612 2016
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 AlteredExpression disease BEFREE BAP1 loss of expression was found in only one lung cancer. 27114369 2016
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 Biomarker disease BEFREE Endogenous HDAC2 directly correlates with BAP1 across a panel of lung cancer cell lines, and is downregulated in mesothelioma cell lines with genetic BAP1 inactivation. 25970771 2015
CUI: C0684249
Disease: Carcinoma of lung
Carcinoma of lung 		0.060 Biomarker disease BEFREE BAP1 resides on human chromosome 3p21.3; intragenic homozygous rearrangements and deletions of BAP1 have been found in lung carcinoma cell lines. 9528852 1998