CASP3, caspase 3, 836

N. diseases: 819; N. variants: 26
Disease: Pancreatic Neoplasm ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.030 Biomarker disease BEFREE Moreover, compared to the pancreatic tumors in C57BL/6J control mice, the tumors in fat-1 transgenic mice treated with sEH inhibitor showed a significant less inflammatory cell infiltrate (62.6±9.2/HPF (high power field) vs. 8.0±1.2/HPF), tumor cell proliferation (48.5±1.7% vs. 16.5±1.6%), and angiogenesis (micro-vessel density (MVD): 35.0±1.0 vs. 11.1±0.5) immunohistochemically, as well as significantly increased caspase-3 labeled apoptosis (0.44±0.06% vs. 0.69±0.06%, respectively). 31262891 2019
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.030 AlteredExpression disease BEFREE P27(Kip1) expression and cleaved caspase-3 are increased, while cyclin E expression is decreased, in S100A4-deficient pancreatic tumors in vivo. 25677816 2015
CUI: C0030297
Disease: Pancreatic Neoplasm
Pancreatic Neoplasm 		0.030 AlteredExpression disease BEFREE Cytoplasmic expression of caspase-3 may be related to the invasiveness of pancreatic tumors. 11075989 2000