B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The effects of AST were mediated through the downregulation of Bcl-2 associated X, apoptosis regulator (Bax), and cleaved caspase-3 and through the upregulation of B-cell lymphoma 2 (Bcl-2).
|
31566218 |
2020 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The protein levels of B-cell lymphoma-2 (Bcl-2), Bcl-2-associated X (Bax), X-linked inhibitor of apoptosis (XIAP), total poly (ADP-ribose) polymerase (PARP), caspase-3 and caspase-8 were examined using western blotting.
|
31586690 |
2020 |
B-Cell Lymphomas
|
0.100 |
Biomarker
|
group |
BEFREE |
Ocimum basilicum L. significantly decreased testicular levels of nuclear factor-kappa B and B-cell lymphoma-2 (Bcl2)-associated protein X, along with caspase-3 immunohistochemical staining.
|
31667861 |
2020 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
After 30 min of ischemia and 120 min of reperfusion, cardiac function, infarct size, cardiac marker enzymes, antioxidative parameters, inflammatory factors, histopathological changes, cardiomyocyte apoptosis, and B‑cell lymphoma 2 (Bcl‑2), Bcl‑2‑associated X protein and caspase‑3 expression were determined using a multi‑channel physiological recording system, nitrotetrazolium blue chloride, biochemical kits, radioimmunoassay kits, hematoxylin and eosin, terminal deoxynucleotidyl‑transferase‑mediated dUTP nick end labeling assay, immunohistochemistry and reverse transcription‑quantitative PCR, respectively.
|
31789417 |
2020 |
B-Cell Lymphomas
|
0.100 |
Biomarker
|
group |
BEFREE |
Furthermore, morin was able to down regulate the levels of inflammatory and apoptotic markers such as nuclear factor kappa B (NF-κB), neuronal nitric oxide synthase (nNOS), tumor necrosis factor-α (TNF-α), p53, cysteine aspartate specific protease-3 (caspase-3) and B-cell lymphoma-2 (Bcl-2).
|
31722249 |
2020 |
B-Cell Lymphomas
|
0.100 |
Biomarker
|
group |
BEFREE |
Western blot analysis was used to investigate the effect of DPM on B-cell lymphoma 2 (Bcl-2), Bcl-2-associated X protein (Bax) and cleaved caspase-3.
|
31553997 |
2020 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
As a result, we observed higher level of XIST and Smurf1, but lower level of miR-27a in SCI rats and lipopolysaccharide (LPS)-induced primary microglial cells. in vitro, LPS induced SCI microglia cells as described by decreased cell viability and B cell lymphoma 2 (Bcl-2) expression, and increased cell apoptosis rate, Bax and cleaved caspase 3 levels, and tumor necrosis factor α (TNF-α) and interleukin 6 (IL-6) secretions. in vivo, a T10 laminectomy caused SCI rats as evidenced by decreased Basso-Beattie-Bresnahan Locomotor Rating Scale (BBB) score and induced expression of Bax, cleaved caspase 3, TNF-α and IL-6.
|
31778769 |
2020 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Furthermore, based on Western blot experiment, cell apoptosis induced by <b>a14</b> also involved the expression of B-cell lymphoma-2 (Bcl-2) family and Caspase 3 protein.
|
31803052 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Meanwhile, oxidative stress induced a significant improvement in the mRNA expression of occludin (OCLN) and caspase-3, and remarkably inhibited the expression of L-type amino acid transporter 1 (LAT1) or B cell lymphoma-2 (Bcl-2), respectively.
|
30891680 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
After transfection of overexpressed miR-590-3p or si-RIPK1, declined RIPK1, NF-κB, Toll-like receptor 4, caspase-3, FasL, p53, and c-myc levels, increased B-cell lymphoma-2 level, promoted cell proliferation, promoted cell cycle distribution and inhibited apoptosis of myocardial cells were found.
|
30321469 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The expression of B‑cell lymphoma (Bcl)‑2, Bcl‑2‑associated X (Bax), and caspase‑3 were detected by western blot analysis and reverse transcription‑quantitative polymerase chain reaction.
|
30628689 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
RT-qPCR and western blot analyses were also performed to determine the effects of miR-210-3p on the expression levels of SIN3A, B-cell lymphoma 2 (Bcl-2) and Caspase-3.
|
31555365 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Moreover, we found enhanced expression of Bcl2-associated X, apoptosis regulator (Bax), and cleaved caspase-3, and reduced expression of B-cell lymphoma 2 (Bcl-2) in the LPS-treated group, which were markedly reversed in the LPS + caffeine co-treated group.
|
31717470 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
B-cell lymphoma (Bcl)-2 mRNA and protein expression levels were decreased however caspase-3, caspase-9 and dynamin-related protein 1 (Drp-1) mRNA and protein expression levels were increased.
|
30867720 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Because PC-corr network inference integrated with a protein-protein interaction network prediction also showed that MURC is involved in the apoptotic pathway, we confirmed the upregulation of STAT3 (signal transducer and activator of transcription 3) and BCL2 (B-cell lymphoma 2) and the inactivation of caspase 3 in I/R-injured hearts of MURC knockout mice compared with those of wild-type mice.
|
31364493 |
2019 |
B-Cell Lymphomas
|
0.100 |
Biomarker
|
group |
BEFREE |
In this study, we identified CD122<sup>high</sup> stem cell antigen-1 (Sca-1) <sup>high</sup> B cell lymphoma 2 (Bcl-2) <sup>high</sup> CD4<sup>+</sup> stem cell-like memory T cells (TSCMs) as a distinct memory T cell subset, which preferentially reside in the BM, where they respond vigorously to blood-borne antigens.
|
30733641 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Immunoblotting demonstrated that levistolide A enhanced doxorubicin‑induced cell death by decreasing the expression levels of B‑cell lymphoma 2 and increasing caspase 3 expression.
|
30483812 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Depletion of ROS by diphenyleneiodonium decreased HG‑induced cell death, and suppressed increases in caspase 3 activity and B‑cell lymphoma 2‑associated X protein levels.
|
30431086 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Furthermore, CBE also prevented UVB-induced apoptosis and significantly downregulated B cell lymphoma 2 (Bcl-2)-associated X, cytochrome-c, and caspase-3 expression, while upregulating Bcl-2 expression.
|
30874982 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
We also found that EEL enhanced the apoptosis of Bel-7402 and Huh-7 cells by regulating the expressions of Bcl-2 associated X (Bax), B cell lymphoma 2 (Bcl-2) and Cytochrome-C and the activity of caspase-3 and therefore promoted cell cycle arrest.
|
31572063 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
At the gene level, CADM1 expression level upregulated caspase-3 activity and expression of Bax and p27 protein and downregulated levels of B cell lymphoma-2, cyclinD1, cyclinE1 and cyclin dependent kinase 2 proteins.
|
30719104 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Furthermore, LncRNA RAB5IF depletion suppressed cell proliferation and colony formation, increased sub G1 population, cleavage of poly ADP-ribose polymerase (PARP) and cysteine aspartyl-specific protease (caspase 3) and attenuated the expression of procaspase 3, pro-PARP and B-cell lymphoma 2 (Bcl-2) in HepG2 and Hep3B cells.
|
31717443 |
2019 |
B-Cell Lymphomas
|
0.100 |
Biomarker
|
group |
BEFREE |
Activation of apoptosis was analyzed by western blot analysis of B‑cell lymphoma 2 (Bcl‑2), Bcl‑2‑associated x protein (Bax), cytochrome c (Cyt c), caspase‑3 and caspase‑9 levels.
|
30431064 |
2019 |
B-Cell Lymphomas
|
0.100 |
Biomarker
|
group |
BEFREE |
The anti-apoptotic proteins B-cell lymphoma 2 (Bcl-2) and Bcl-xL were significantly upregulated, whereas the pro-apoptotic proteins BCL2-associated X (Bax), H<sub>2</sub>O<sub>2</sub>-induced cleaved caspase-3, and the DNA damage marker, phosphorylated histone (γH2A.X) foci, were significantly downregulated upon histochrome treatment of hCPCs in vitro.
|
31234277 |
2019 |
B-Cell Lymphomas
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Furthermore, the expression of anti-apoptotic protein B-cell lymphoma 2 decreased and the expression of the pro-apoptotic proteins active caspase-3 and apoptosis regulator BAX increased in the Hep G2 cells following JTC-801 treatment.
|
30675258 |
2019 |