CASP3, caspase 3, 836

N. diseases: 722; N. variants: 20
Disease: Histiocytic sarcoma ×
Source: BEFREE ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334663
Disease: Histiocytic sarcoma
Histiocytic sarcoma 		0.010 Biomarker disease BEFREE The human histiocytic lymphoma cell line (U937) also responds to JP-8 with caspase-3 activation, cleavage of caspase substrates, including PARP, DNA-PK, and lamin B1, and degradation of genomic DNA with the production of HMW fragments. 11222085 2001