CASP3, caspase 3, 836

N. diseases: 819; N. variants: 26
Disease: Brain Infarction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0751955
Disease: Brain Infarction
Brain Infarction 		0.010 AlteredExpression disease BEFREE Treatment of XQ-1H (78 or 39 mg/kg, i.g., bid) 2 h after MCAO improved motor skills and ameliorated the severity of brain infarction and apoptosis seen in the mice by diminishing pathological changes and the activation of a pro-apoptotic protein Cleaved-Caspase-3, which in turn induced anti-apoptotic Bcl-xL. 31499069 2019