CASP6, caspase 6, 839

N. diseases: 73; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 Biomarker group BEFREE Caspase-6 (casp6) in particular has been shown to play a key role in the pathogenesis of stroke, Huntington disease, and Alzheimer disease. 29193273 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 AlteredExpression group BEFREE Decreasing CASP6 activity may help to restore neuronal function in these and other diseases such as stroke and ischemia, where increased CASP6 activity has been implicated. 27911442 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.030 Biomarker group BEFREE Intranasal delivery of caspase-9 inhibitor reduces caspase-6-dependent axon/neuron loss and improves neurological function after stroke. 21677173 2011