PLA2G10, phospholipase A2 group X, 8399

N. diseases: 86; N. variants: 0
Disease: Astrocytoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.030 Biomarker disease BEFREE Herein, to understand the underlying relationship between obesity and brain tumors, we investigated the effect of leptin, alone or in combination with sPLA2-IIA on astrocytoma cell functions. sPLA2-IIA induced up-regulation of leptin receptors in 1321N1 human astrocytoma cells. 28249041 2017
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.030 Biomarker disease BEFREE In this study, we used human astrocytoma 1321N1 cells to investigate the key molecules mediating sPLA(2)-IIA-induced cell proliferation. 19737348 2009
CUI: C0004114
Disease: Astrocytoma
Astrocytoma 		0.030 Biomarker disease BEFREE Inflammatory protein sPLA(2)-IIA abrogates TNFalpha-induced apoptosis in human astroglioma cells: Crucial role of ERK. 19850087 2009