PLA2G10, phospholipase A2 group X, 8399

N. diseases: 86; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.040 AlteredExpression group BEFREE Prospective cohort of 1735 children (45% females) who had serum sPLA2 enzyme activity levels and other cardiovascular disease risk factors measured in 1980 that were followed-up in 2001. 29476705 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.040 Biomarker group BEFREE Our results suggest that selective targeting of individual sPLA2 enzymes may be a better strategy to treat cardiovascular diseases. 23349189 2013
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.040 Biomarker group BEFREE Hazard ratios (HR) were compared with those expected if the association between sPLA(2)-IIa and CVD were causal. 21799821 2011
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.040 AlteredExpression group BEFREE Our data indicate that increased expression of sPLA(2) might represent a novel causative risk factor contributing to the increased cardiovascular disease morbidity and mortality in ESRD. 19798476 2010