MAGT1, magnesium transporter 1, 84061

N. diseases: 120; N. variants: 8
Disease: Lymphoproliferative Syndrome, X-Linked, 2 ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1845076
Disease: Lymphoproliferative Syndrome, X-Linked, 2
Lymphoproliferative Syndrome, X-Linked, 2 		0.010 Biomarker disease BEFREE IAP inhibition or loss of both cIAP2 and XIAP resulted in a strong blockage in autophagic flux and mitophagy, suggesting that XIAP deficiency may also drive Crohn's Disease due to defects in autophagy. 29743550 2018