CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027430
Disease: Nasal Polyps
Nasal Polyps
0.030 Biomarker disease BEFREE Microarray analysis revealed an increased gene expression of eNOS (1.40-fold) as well as a decreased gene expression of NOSTRIN (0.53-fold) and CASP8 (0.44-fold) in nasal polyps. 29885366 2018
CUI: C0027430
Disease: Nasal Polyps
Nasal Polyps
0.030 Biomarker disease BEFREE MTX-treated NPs contained significantly increased amounts of the active forms of caspase 8, caspase 9, and caspase 3 and displayed increased cleavage of poly(ADP-ribose) polymerase. 23406595 2013
CUI: C0027430
Disease: Nasal Polyps
Nasal Polyps
0.030 Biomarker disease BEFREE PCNA was more frequently expressed in IP compared to NE (p=0.04) and caspase-8 and bax staining were less frequently observed in IP compared to NP (p=0.004 and p=0.01 respectively) and NE (p=0.003 and p=0.01, respectively). 22560505 2012