CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Disease: Germinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206660
Disease: Germinoma
Germinoma 		0.010 Biomarker disease BEFREE Epigenetic silencing of a large number of potential tumour suppressor genes in YSTs might explain why they exhibit a more aggressive natural history than germinomas and silencing of genes associated with Caspase-8-dependent cell death might explain the relative resistance of YSTs to conventional therapy. 21712824 2011