CASP8, caspase 8, 841

N. diseases: 480; N. variants: 32
Disease: Multiple tumors ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0260037
Disease: Multiple tumors
Multiple tumors 		0.010 GeneticVariation phenotype BEFREE Polymorphisms in CASP8 at 2q33.1 have been associated with the risk of developing cancer, specifically, the D302H variant (rs1045485) with breast cancer in the European population and the -652 6N ins/del promoter variant (rs3834129) with multiple tumours including colorectal cancer (CRC) in the Chinese population. 18362937 2008