Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
These results emphasize on the relevance of the correct identification of atypical PML-RAR(alpha) rearrangements because of the potential implications in leukemogenesis, in the response to treatment, and for the correct monitoring of minimal residual disease.
|
11916515 |
2002 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Prognostic significance of minimal residual disease detection and PML/RAR-alpha isoform type: long-term follow-up in acute promyelocytic leukemia.
|
11675334 |
2001 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Monitoring of minimal residual disease (MRD) was performed regularly by RT-PCR assay for PML-RAR alpha during consolidation.
|
11775836 |
2000 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Prolonged molecular remission after PML/RAR alpha-positive autologous peripheral blood stem cell transplantation in acute promyelocytic leukemia: is relevant pretransplant minimal residual disease in the graft?
|
9639431 |
1998 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Minimal residual disease in acute myelogenous leukemia with PML/RAR alpha or AML1/ETO mRNA and phenotypic analysis of possible T and natural killer cells in bone marrow.
|
9643569 |
1998 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Reverse transcription polymerase chain reaction of the PML-RAR alpha rearrangement is useful for the monitoring of minimal residual disease.
|
9045308 |
1997 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Quantification of PML-RAR alpha transcripts in acute promyelocytic leukaemia: explanation for the lack of sensitivity of RT-PCR for the detection of minimal residual disease and induction of the leukaemia-specific mRNA by alpha interferon.
|
8857944 |
1996 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
RT-PCR analysis for the PML/RAR alpha rearrangement was performed to monitor patients for evidence of minimal residual disease.
|
7845010 |
1995 |
Neoplasm, Residual
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
To assess the presence of minimal residual disease (MRD) and the contamination of leukemic cells in peripheral stem cells (PSCs), we examined six patients with APL who were undergoing PSCT, using reverse transcriptase polymerase chain reaction analysis to detect the mRNA of the PML/RAR alpha fusion gene.
|
7539517 |
1995 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Recent development of a reverse-transcription polymerase chain reaction (RT-PCR) assay for the PML/RAR-alpha hybrid has proven useful for rapid diagnosis and monitoring of minimal residual disease (MRD) in APL patients.
|
7518548 |
1994 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Recent development of a reverse-transcription polymerase chain reaction (RT-PCR) assay for the PML/RAR-alpha hybrid has proven useful for rapid diagnosis and monitoring of minimal residual disease (MRD) in APL patients.
|
7815841 |
1994 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
The reverse transcriptase-polymerase chain reaction (RT-PCR) for the fusion transcript of PML-RAR alpha can be used to detect minimal residual disease (MRD) in acute promyelocytic leukemia (APL).
|
8289472 |
1994 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Acute promyelocytic leukemia: clinical relevance of two major PML-RAR alpha isoforms and detection of minimal residual disease by retrotranscriptase/polymerase chain reaction to predict relapse.
|
8394752 |
1993 |
Neoplasm, Residual
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Detection of minimal residual disease in acute promyelocytic leukemia by a reverse transcription polymerase chain reaction assay for the PML/RAR-alpha fusion mRNA.
|
8400225 |
1993 |
Neoplasm, Residual
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
In this study, 9 patients (pts) with acute promyelocytic leukemia (APL) in long-term remission for 4 to 12 years were analyzed for the presence of MRD by RT-PCR amplification of the specific PML/RAR-alpha fusion gene.
|
8260693 |
1993 |