Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038580
Disease: Substance Dependence
Substance Dependence
0.010 Biomarker disease BEFREE CKIepsilon phosphorylates and activates DARPP-32, a key molecule in various complex signaling pathways, including dopamine and glutamine signaling, which have both been demonstrated to be main pathways in substance dependence. 18991847 2008