ANTXR1, ANTXR cell adhesion molecule 1, 84168

N. diseases: 137; N. variants: 22
Disease: Breast Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.140 Biomarker disease BEFREE We show that the loss of TEM8 in cancer cells results in inhibition of cancer progression, reduction in tumor angiogenesis and reduced metastatic burden in breast cancer mouse models. 30046396 2018
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.140 GeneticVariation disease GWASCAT Association analysis identifies 65 new breast cancer risk loci. 29059683 2017
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.140 Biomarker disease BEFREE The anthrax toxin receptor 1 (ANTXR1) has been identified as a functional biomarker of normal stem cells and breast cancer stem-like cells. 23832666 2013
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.140 Biomarker disease BEFREE Mice transgenic for the rat neu proto-oncogene were immunized with DNA vaccines encoding TEM8 and the extracellular domain of rat neu and challenged with the 233-VSGA1 breast cancer cell line. 17361485 2007
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.140 Biomarker disease BEFREE TEM-8 was detected in a variety of breast cancer cell lines, endothelial cells (HECV) and in a human fibroblast cell line (MRC5) at both the mRNA and protein level. 17016666 2006