CASP9, caspase 9, 842

N. diseases: 293; N. variants: 22
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.220 Therapeutic disease RGD Glutamine reduces myocardial cell apoptosis in a rat model of sepsis by promoting expression of heat shock protein 90. 29180187 2017
CUI: C0243026
Disease: Sepsis
Sepsis
0.220 AlteredExpression disease BEFREE An over-expression of Caspase-9 and pro-apoptotic protein Bax was found in lymphocytes of cirrhotic patients with infection or sepsis as compared with non-infected cases (P = 0.05 and 0.0001, respectively), while anti-apoptotic proteins Bcl-2 and Bcl-xL were downregulated. 23590253 2013
CUI: C0243026
Disease: Sepsis
Sepsis
0.220 AlteredExpression disease BEFREE Delayed neutrophil apoptosis in sepsis is associated with maintenance of mitochondrial transmembrane potential and reduced caspase-9 activity. 15241089 2004