DCTN5, dynactin subunit 5, 84516

N. diseases: 8; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 GeneticVariation disease BEFREE We also examined the utility of this assay system in bipolar disorder (BD), which has a strong genetic overlap with schizophrenia, by examining the bipolar disorder susceptibility gene Dctn5. 21440632 2011
CUI: C0005586
Disease: Bipolar Disorder
Bipolar Disorder
0.310 Biomarker disease PSYGENET We also examined the utility of this assay system in bipolar disorder (BD), which has a strong genetic overlap with schizophrenia, by examining the bipolar disorder susceptibility gene Dctn5. 21440632 2011
CUI: C0200635
Disease: Lymphocyte Count measurement
Lymphocyte Count measurement
0.100 GeneticVariation phenotype GWASDB The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes. 22286170 2012
CUI: C0025202
Disease: melanoma
melanoma
0.010 Biomarker disease BEFREE CONCLUSIONS Our findings suggest that downregulated DCTN1, DCTN2, and DCTN5 and upregulated DCTN6 mRNA expression in CM are associated with favorable prognosis and may represent potential prognostic biomarkers. 29864111 2018
CUI: C0151779
Disease: Cutaneous Melanoma
Cutaneous Melanoma
0.010 Biomarker disease BEFREE CONCLUSIONS Our findings suggest that downregulated DCTN1, DCTN2, and DCTN5 and upregulated DCTN6 mRNA expression in CM are associated with favorable prognosis and may represent potential prognostic biomarkers. 29864111 2018
CUI: C0003872
Disease: Arthritis, Psoriatic
Arthritis, Psoriatic
0.010 Biomarker disease BEFREE By using exome sequencing and extreme phenotype design, it was recently shown that isoforms of dynactin 4 (DCTN4) may influence Pa infection in CF, leading to worse respiratory disease. 25763772 2016
CUI: C0010674
Disease: Cystic Fibrosis
Cystic Fibrosis
0.010 Biomarker disease BEFREE By using exome sequencing and extreme phenotype design, it was recently shown that isoforms of dynactin 4 (DCTN4) may influence Pa infection in CF, leading to worse respiratory disease. 25763772 2016
CUI: C0035204
Disease: Respiration Disorders
Respiration Disorders
0.010 GeneticVariation group BEFREE By using exome sequencing and extreme phenotype design, it was recently shown that isoforms of dynactin 4 (DCTN4) may influence Pa infection in CF, leading to worse respiratory disease. 25763772 2016
CUI: C0035242
Disease: Respiratory Tract Diseases
Respiratory Tract Diseases
0.010 GeneticVariation group BEFREE By using exome sequencing and extreme phenotype design, it was recently shown that isoforms of dynactin 4 (DCTN4) may influence Pa infection in CF, leading to worse respiratory disease. 25763772 2016