FOXN1, forkhead box N1, 8456

N. diseases: 60; N. variants: 5
Disease: Alopecia universalis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0263505
Disease: Alopecia universalis
Alopecia universalis 		0.010 GeneticVariation disease BEFREE Investigation of a patient with a rare homozygous FOXN1 mutation (R255X), leading to alopecia universalis and thymus aplasia, unexpectedly revealed non-maternal circulating T-cells, and, strikingly, large numbers of aberrant double-negative αβ T-cells (CD4negCD8neg, DN) and regulatory-like T-cells. 22590644 2012