CASR, calcium sensing receptor, 846

N. diseases: 517; N. variants: 131
Disease: tumor vasculature ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.020 Biomarker phenotype BEFREE It is therefore hypothesized that targeting CAR T cells towards the tumor vasculature of solid tumors may share the excellent effects of CAR T cell therapy with that against hematological malignancies. 31628559 2019
CUI: C1658953
Disease: tumor vasculature
tumor vasculature 		0.020 AlteredExpression phenotype BEFREE Mouse and human T cells were engineered to express a chimeric antigen receptor (CAR) targeted against VEGFR-2, which is overexpressed in tumor vasculature and is responsible for VEGF-mediated tumor progression and metastasis. 20978347 2010