CASR, calcium sensing receptor, 846

N. diseases: 517; N. variants: 131
Disease: IMMUNE SUPPRESSION ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1840264
Disease: IMMUNE SUPPRESSION
IMMUNE SUPPRESSION 		0.010 Biomarker phenotype BEFREE Despite remarkable success in the treatment of hematological malignancies, CAR T-cell therapies for solid tumors have floundered, in large part due to local immune suppression and the effects of prolonged stimulation leading to T-cell dysfunction and exhaustion. 31727131 2019