NT5C1A, 5'-nucleotidase, cytosolic IA, 84618

N. diseases: 63; N. variants: 1
Disease: Chronic rejection of renal transplant ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0403592
Disease: Chronic rejection of renal transplant
Chronic rejection of renal transplant 		0.010 GeneticVariation disease BEFREE These results are in agreement with in vitro data suggesting that CD28 is a major co-stimulatory signal of both Tregs development and peripheral homeostasis but contrast with clinical trials showing a better 1-year graft function and a lower incidence of chronic allograft nephropathy in patients receiving Belatacept than patients treated with CNI. 20667993 2011