TRIM63, tripartite motif containing 63, 84676

N. diseases: 73; N. variants: 4
Disease: Muscle damage ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0410158
Disease: Muscle damage
Muscle damage 		0.020 Biomarker phenotype BEFREE TRIM63 (MuRF-1) gene polymorphism is associated with biomarkers of exercise-induced muscle damage. 29212849 2018
CUI: C0410158
Disease: Muscle damage
Muscle damage 		0.020 AlteredExpression phenotype BEFREE Decreased maximal jump height and increased serum creatine kinase activities as indirect markers for muscle damage and HSP27 immunostainings on muscle biopsies as a direct marker for muscle damage indicated that the current exercised protocol caused muscle damage. mRNA levels for four (MLP, Ankrd1/CARP, MuRF1 and MuRF2) out of the five studied stress sensors significantly (p < 0.05) increased 3 h after fatiguing exercise. 28712031 2017