|
Nephroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Ginger oil elevated the CAT and SOD (antioxidant enzymes), serum testosterone and diminished the oxidative stress, up regulated the expression of Vegfa and Sycp3 and down-regulated the Wt1 expression.
|
30530043 |
2019 |
|
Nephroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
At 11p13, the frequencies of LOH were 20% (9/46) at the FSHB locus, 9% (5/53) at the WT1 locus, and 15% (6/41) at the CAT locus.
|
7522041 |
1994 |
|
Nephroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A high incidence of loss of heterozygosity (LOH) was found with the probe for catalase (21/29), a locus flanking the centromeric region of the Wilms' tumor locus.
|
1682278 |
1991 |
|
Nephroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Human mapping studies have shown that the aniridia (AN2) gene, which is part of the Wilms tumor susceptibility, aniridia, genitourinary abnormalities, and mental retardation (WAGR) complex, is also between FSHB and CAT on human chromosome 11.
|
2347591 |
1990 |
|
Nephroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These studies allowed the regional assignment of the gene for catalase, which is linked to the Wilms tumor locus, between MIC4 and MIC11, two loci encoding for membrane antigens previously mapped to band 11p13.
|
2536636 |
1989 |
|
Nephroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Nine of these clones map to 11p13, and four of the nine [57(D11S89), 530(D11S90), 706(D11S93), and 1104(D11S95)] are confined to the same segment within p13 that contains catalase (CAT), the beta subunit of follicle stimulating hormone (FSHB), and the Wilms' tumor-aniridia (WAGR) gene complex.
|
2852164 |
1988 |
|
Nephroblastoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Because of the proximity of the two gene loci, assays of erythrocyte CAT may be useful to identify a submicroscopic deletion in some patients with sporadic aniridia and to predict a risk of developing Wilms tumor.
|
6325323 |
1984 |
|
Nephroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Catalase determination in various etiologic forms of Wilms' tumor and gonadoblastoma.
|
6309358 |
1983 |
|
Nephroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The patients were otherwise clinically normal and without signs of Wilms' tumor; their erythrocyte catalase activities were within the normal range.
|
6301974 |
1983 |
|
Nephroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
These findings confirmed a close linkage of the gene for catalase and those for the aniridia--Wilm's tumor or gonadoblastoma complex.
|
7106775 |
1982 |
|
Nephroblastoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We studied the RBC catalase levels in individuals without detectable chromosomal abnormalities but with aniridia, Wilm's tumor, and the combination of aniridia and Wilms' tumor, to determine whether catalase levels might provide evidence for a submicroscopic chromosomal deletion in the 11p13 region.
|
6273073 |
1981 |
|
Nephroblastoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Regional assignment of catalase (CAT) gene to band 11p13. Association with the aniridia-Wilms' tumor-Gonadoblastoma (WAGR) complex.
|
6252821 |
1980 |