CAT, catalase, 847

N. diseases: 794; N. variants: 14
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma
0.020 Biomarker disease BEFREE We propose potentiation of reduced GSH, GR, and catalase in glioblastoma cells through NMDAR as a novel rationale of chemoresistance in glioblastoma. 31187913 2019
CUI: C0278878
Disease: Adult Glioblastoma
Adult Glioblastoma
0.020 AlteredExpression disease BEFREE In the present study non-cytotoxic dose of oxidants, H<sub>2</sub>O<sub>2</sub> (100 μM) and GO (10 μU/ml) was used to induce moderate oxidative stress via generating ROS in human glioblastoma cell line U-87 MG cells, which showed a marked increase in the antioxidant capacity as studied by measuring the modulation in expression levels and activities of superoxide dismutase (SOD1 and SOD2) and catalase (CAT) enzymes, and the GSH content. 28676971 2017