|
Depressed mood
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Modulation of catalase, copper and zinc in the hippocampus and the prefrontal cortex in social isolation-induced depression in male rats.
|
31342954 |
2019 |
|
Depressed mood
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Moreover, in the APAP groups, a marked depression was recorded in the t-SH and GSH levels and GPx and CAT activities at PND 40 in the neonatal liver compared to those in the control group.
|
30760194 |
2019 |
|
Depressed mood
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Patients completed a measure of the magnitude of physical limitations (Patient-Reported Outcomes Measurement Information System [PROMIS] Physical Function Computerized Adaptive Test [CAT]), a measure of the degree to which a person limits activities owing to pain (PROMIS Pain Interference CAT), and a measure of symptoms of depression (PROMIS Depression CAT) at every office visit.
|
29908926 |
2019 |
|
Depressed mood
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Patients in stable COPD with high CAT scores and depression were most likely to experience new-onset exhaustion episodes Thus, exhaustion might be predicted by a combination of psychological factors and respiratory health status.
|
29436160 |
2018 |
|
Depressed mood
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Statistically significant correlations were found with HADS (anxiety r=.608 and depression r=.615), mMRC dyspnea (r=.592), 6MWT (r=-0.445), FEV1 (r=-0.312), all dimensions of CRQ-SAS (dyspnea r=-0.626; fatigue r=-0.718; emotional function r=-0.663; mastery r=-0.740), CAT (r=0.669), and baseline dyspnea index (r=-0.615).
|
29122333 |
2018 |
|
Depressed mood
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
The multivariate model of variables independently associated with CAT included depression, dysfunctional breathing symptoms (Nijmegen score), and illness perception, in addition to COPD symptoms (wheeze, cough), exercise capacity, breathlessness, exacerbations, and deprivation; this model explained 72% of CAT score variation.
|
29386893 |
2018 |
|
Depressed mood
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
Concluding, the studied polymorphisms of SOD2, CAT and GPx4 may modulate the risk of depression.
|
29331597 |
2018 |
|
Depressed mood
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
Moreover, a simulation CAT study with real response data was conducted to investigate the characteristics, marginal reliability, criterion-related validity, and predictive utility (sensitivity and specificity) of CAT-Depression.
|
30072935 |
2018 |
|
Depressed mood
|
0.100 |
Biomarker
|
phenotype |
BEFREE |
It has been shown that asymmetric dimethylarginine (ADMA), carbonyl groups, catalase (CAT) and neurokinin A (NKA) are actively involved in neuronal processes such as depression and posttraumatic stress disorder (PTSD).
|
28554099 |
2017 |
|
Depressed mood
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
The mechanism of its antitumor effect involved in (a) reducing oxidative stress injury through up-regulating activities of CAT and SOD; (b) down-regulating the levels of inflammatory factors, like TNF-α, IL6, COX-2, and PGE2; (c) activation of caspase-3 and up-regulating the pro-apoptotic protein Bax; (d) decreasing the expression of PCNA; (e) depressing the expression of cancer stem cells marker CD133; (f) suppressing aberrant expression of cytokeratin 8 and 18; and (g) inhibiting EGFR/ PI3 K/Akt, EGFR/Ras/Erk and NF-κB pathways.
|
27991692 |
2017 |
|
Depressed mood
|
0.100 |
GeneticVariation
|
phenotype |
BEFREE |
There is a significant association between depression and polymorphisms in O&NS genes, like manganese superoxide dismutase, catalase, and myeloperoxidase.
|
20471444 |
2011 |
|
Depressed mood
|
0.100 |
AlteredExpression
|
phenotype |
BEFREE |
Depression of catalase gene expression in the liver of tumor bearing nude mice.
|
1472018 |
1992 |