IRS4, insulin receptor substrate 4, 8471

N. diseases: 35; N. variants: 0
Disease: Mammary Tumorigenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1512981
Disease: Mammary Tumorigenesis
Mammary Tumorigenesis 		0.010 Biomarker phenotype BEFREE IRS4 induces mammary tumorigenesis and confers resistance to HER2-targeted therapy through constitutive PI3K/AKT-pathway hyperactivation. 27876799 2016