Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 AlteredExpression disease BEFREE We aimed to evaluate the differential expression of TIM-3 between the primary and metastatic sites of RCC. 30630458 2019
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 Biomarker disease BEFREE In the present study, the role of Tim‑3 in anoikis and its influence on the invasion of clear cell renal cell carcinoma (ccRCC) was investigated. 28112366 2017
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 Biomarker disease BEFREE Using the VectraR automated multiparametric immunofluorescence technique, we quantified intratumoral CD8<sup>+</sup> T cells coexpressing the inhibitory receptors PD-1 and Tim-3 from patients with renal cell carcinoma (RCC). 27872087 2017
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 Biomarker disease BEFREE Blocking the Tim-3 pathway restored cell proliferation and increased IFN-γ production in TIL CD4+ and CD8+ T cells of RCC. 26253654 2016
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 AlteredExpression disease BEFREE TIM-3 protein was expressed in both ccRCC cell lines. 24195506 2014
Conventional (Clear Cell) Renal Cell Carcinoma
0.060 Biomarker disease BEFREE These results suggest that polymorphisms in the TIM-3 gene are new risk factors for RCC and that TIM-3 may play important roles in regulating the prognosis of this disease. 22472081 2012