RSPO3, R-spondin 3, 84870

N. diseases: 64; N. variants: 22
Disease: Intestinal Cancer ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346627
Disease: Intestinal Cancer
Intestinal Cancer 		0.020 Biomarker disease BEFREE The combination of RSPO3 inhibition and taxane treatment provides an approach to effectively target oncogenic WNT signaling in a significant number of patients with colorectal and other intestinal cancers. 29127379 2017
CUI: C0346627
Disease: Intestinal Cancer
Intestinal Cancer 		0.020 Biomarker disease BEFREE The current study determines the extent into which solely a gain in RSPO3 actually functions as a driver of intestinal cancer in a direct, causal fashion, and addresses the in vivo activities of RSPO3 in parallel. 27511199 2017