RSPO3, R-spondin 3, 84870

N. diseases: 64; N. variants: 22
Disease: Traditional Serrated Adenoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1266025
Disease: Traditional Serrated Adenoma
Traditional Serrated Adenoma 		0.020 AlteredExpression disease BEFREE Reverse transcription PCR identified previously reported PTPRK-RSPO3 fusion transcripts in all 29 TSAs with RSPO3 overexpression, confirming that PTPRK-RSPO3 is the predominant RSPO fusion in TSAs. 30916365 2019
CUI: C1266025
Disease: Traditional Serrated Adenoma
Traditional Serrated Adenoma 		0.020 Biomarker disease BEFREE In addition, rapid amplification of cDNA ends revealed three novel RSPO fusion transcripts, an NRIP1-RSPO2 fusion and two PTPRK-RSPO3 fusion isoforms, in six TSAs. 28543708 2017