RGS5, regulator of G protein signaling 5, 8490

N. diseases: 52; N. variants: 5
Disease: Tumor Angiogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.020 Biomarker phenotype BEFREE Regulator of G protein signaling 5 (RGS5) belongs to the R4 subfamily of RGS proteins, a family of GTPase activating proteins, which is dynamically regulated in various biological processes including blood pressure regulation, smooth muscle cell pathology, fat metabolism and tumor angiogenesis. 25891540 2015
CUI: C1519670
Disease: Tumor Angiogenesis
Tumor Angiogenesis 		0.020 AlteredExpression phenotype BEFREE Elevated levels of RGS-5 in pericytes are also observed during wound healing and ovulation indicating a strong correlation between RGS-5 expression and active vessel remodeling beyond tumor angiogenesis. 15459006 2005