Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.040 AlteredExpression group BEFREE The pathogenic mechanism of autoimmune disease by GLK overexpression was unraveled by characterizing T-cell-specific GLK transgenic mice and using biochemical analyses. 31640697 2019
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.040 Biomarker group BEFREE T cell-specific GLK transgenic mice spontaneously developed autoimmune diseases with selective induction of IL-17A in T cells. 30214937 2018
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.040 Biomarker group BEFREE T-cell-mediated immune responses and Th17-mediated experimental autoimmune diseases are enhanced in HPK1 knockout mice but ameliorated in GLK knockout mice. 26791862 2016
CUI: C0004364
Disease: Autoimmune Diseases
Autoimmune Diseases
0.040 Biomarker group BEFREE GLK overexpression in T cells contributes to the pathogenesis of RA, indicating that GLK is a novel biomarker for autoimmune disease severity and a potential therapeutic target for RA. 23817999 2013