Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 AlteredExpression disease BEFREE KPNA2 overexpression could partially rescue Wip1 silence-inhibited CRC cell proliferation and migration. 31127650 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 Biomarker disease BEFREE The truncating mutations (nonsense and frameshift) in exon 6 of PPM1D were found recently in blood cells of patients with breast, ovarian or colorectal cancer. 25742468 2015
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 AlteredExpression disease BEFREE Wip1 mRNA and protein are highly expressed in colorectal cancers and may be associated with colorectal cancer development and progression. 23679302 2013
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 Biomarker disease BEFREE We found that PPM1D plays a crucial role in colorectal carcinoma cell proliferation and colony formation. 23745790 2013
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.050 AlteredExpression disease BEFREE Significantly reduced mRNA expression of Wip1, B4-2, and cofilin in stomach cancers, of Wip1, B4-2, BRCA-2 region transcription unit CG005, cofilin, and ROCK in colorectal cancers, and of TROP2, B4-2, and BRCA-2 region transcription unit CG005 in HCCs, was observed in comparison with the corresponding non-cancerous tissues, whereas overexpression of TROP2 was detected in colorectal cancers. 11768609 2001