RUNX2, RUNX family transcription factor 2, 860

N. diseases: 405; N. variants: 37
Disease: bone destruction ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0238790
Disease: bone destruction
bone destruction 		0.010 AlteredExpression disease BEFREE MiR-223 and miR-19a were found to regulate the expression of TWIST and Runx2, influence the RANKL-RANK pathway and the expression of MCP-1, and finally regulate the pathophysiological process of osteolytic bone destruction. 30309658 2018