|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
Cytogenetic patterns in ETV6/RUNX1-positive pediatric B-cell precursor acute lymphoblastic leukemia: A Nordic series of 245 cases and review of the literature.
|
17285576 |
2007 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.
|
24413735 |
2014 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The CBFA2 gene at 21q22 is also frequently disrupted in de novo ALL and AML and less commonly in secondary AML.
|
10825008 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Quantitative multiparametric immunophenotyping in acute lymphoblastic leukemia: correlation with specific genotype. I. ETV6/AML1 ALLs identification.
|
10914546 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
The complex genomic profile of ETV6-RUNX1 positive acute lymphoblastic leukemia highlights a recurrent deletion of TBL1XR1.
|
18767146 |
2008 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
LHGDN |
TEL-AML1 fusion precedes differentiation to pre-B cells in childhood acute lymphoblastic leukemia.
|
12526921 |
2003 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.
|
7780150 |
1995 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The procedure was tested with CD10(+) acute lymphoblastic leukemia cell line harboring the t(12;21)(p13;q22) resulting in the ETV6/RUNX1 rearrangement (formerly TEL/AML1), as well as peripheral blood lymphocytes of healthy individuals.
|
17284366 |
2007 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Prognostic impact of RUNX1 and ETV6 gene copy number on pediatric B-cell precursor acute lymphoblastic leukemia with or without hyperdiploidy.
|
27393278 |
2016 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
ETV6/RUNX1 rearrangement in childhood B-precursor acute lymphoblastic leukemia with normal karyotypes or without cytogenetic results.
|
15193447 |
2004 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The final three sections of the chapter cover the spectrum and clinical significance of RUNX1 point mutations in AML and myelodysplastic syndromes, in familial platelet disorder with associated myeloid malignancy, and in acute lymphoblastic leukemia.
|
28299658 |
2017 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Involvement of der(12)t(12;21)(p13;q22) and as well as additional rearrangements of chromosome 12 homolog in ETV6/RUNX1-positive acute lymphoblastic leukemia.
|
19264230 |
2009 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Overexpression of PTP4A3 in ETV6-RUNX1 acute lymphoblastic leukemia.
|
28063378 |
2017 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
ETV6/CBFA2 fusions in childhood B-cell precursor acute lymphoblastic leukemia with myeloid markers.
|
11129441 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
|
11455977 |
2001 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Abnormalities of the der(12)t(12;21) in ETV6-RUNX1 acute lymphoblastic leukemia.
|
23077088 |
2013 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Expression of TEL-AML1 fusion transcripts and response to induction therapy in standard risk acute lymphoblastic leukemia.
|
11699220 |
2001 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
High incidence of TEL/AML1 fusion resulting from a cryptic t(12;21) in childhood B-lineage acute lymphoblastic leukemia in Taiwan.
|
8667657 |
1996 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The ETV6/CBFA2 (TEL/AML1) fusion gene occurs as a result of the chromosome translocation t(12;21)(p13;q22) in up to 30% of children diagnosed with B cell precursor (cd10+, cd19+) acute lymphoblastic leukemia.
|
9050885 |
1997 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Genetic abnormalities involved in t(12;21) TEL-AML1 acute lymphoblastic leukemia: analysis by means of array-based comparative genomic hybridization.
|
17374122 |
2007 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The t(12;21)(p13;q22) chromosomal translocation is the most frequent translocation in childhood B cell precursor-acute lymphoblastic leukemia and results in the expression of an ETV6/RUNX1 fusion protein.
|
24339741 |
2013 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Detection of ETV6 and RUNX1 gene rearrangements using fluorescence in situ hybridization in Mexican patients with acute lymphoblastic leukemia: experience at a single institution.
|
16213362 |
2005 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Translocation (2;8)(p12;q24) associated with a cryptic t(12;21)(p13;q22) TEL/AML1 gene rearrangement in a child with acute lymphoblastic leukemia.
|
11106815 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Clonal origins of ETV6-RUNX1⁺ acute lymphoblastic leukemia: studies in monozygotic twins.
|
25388957 |
2015 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Cloning and sequencing of ETV6/RUNX1 (TEL/AML1) variant in acute lymphoblastic leukemia.
|
15104290 |
2004 |