|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia.
|
7761424 |
1995 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The t(12;21) of acute lymphoblastic leukemia results in a tel-AML1 gene fusion.
|
7780150 |
1995 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
High incidence of TEL/AML1 fusion resulting from a cryptic t(12;21) in childhood B-lineage acute lymphoblastic leukemia in Taiwan.
|
8667657 |
1996 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
TEL-AML1 fusion RNA as a new target to detect minimal residual disease in pediatric B-cell precursor acute lymphoblastic leukemia.
|
8704188 |
1996 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Lack of TEL-AML1 fusion transcript resulting from a cryptic t(12;21) in adult B lineage acute lymphoblastic leukemia in Taiwan.
|
8751462 |
1996 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Correlation between the ETV6/CBFA2 (TEL/AML1) fusion gene and karyotypic abnormalities in children with B-cell precursor acute lymphoblastic leukemia.
|
8913730 |
1996 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The ETV6/CBFA2 (TEL/AML1) fusion gene occurs as a result of the chromosome translocation t(12;21)(p13;q22) in up to 30% of children diagnosed with B cell precursor (cd10+, cd19+) acute lymphoblastic leukemia.
|
9050885 |
1997 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Münster Study Group.
|
9226156 |
1997 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Other relevant characteristics of TEL/AML1-positive ALL are frequent deletion of the other TEL allele and association with an excellent prognostic outcome.
|
9234595 |
1997 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Incidence of TEL/AML1 fusion in children with relapsed acute lymphoblastic leukemia.
|
9845546 |
1998 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Acute myelogenous leukemia with monosomy 7, inv(3) (q21q26), involving activated EVI 1 gene occurring after a complete remission of lymphoblastic lymphoma: a case report.
|
9861236 |
1998 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The t(12;21)(p13;q22) translocation, fusing the ETV6 and AML1 genes, is the most frequent chromosomal translocation associated with pediatric B-cell precursor acute lymphoblastic leukemia.
|
9864173 |
1999 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Low frequency of TEL-AML1 in relapsed acute lymphoblastic leukemia supports a favorable prognosis for this genetic subgroup.
|
10049054 |
1999 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
TEL-AML1 fusion identifies a subset of children with standard risk acute lymphoblastic leukemia who have an excellent prognosis when treated with therapy that includes a single delayed intensification.
|
10557042 |
1999 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The CBFA2 gene at 21q22 is also frequently disrupted in de novo ALL and AML and less commonly in secondary AML.
|
10825008 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Quantitative multiparametric immunophenotyping in acute lymphoblastic leukemia: correlation with specific genotype. I. ETV6/AML1 ALLs identification.
|
10914546 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Translocation (2;8)(p12;q24) associated with a cryptic t(12;21)(p13;q22) TEL/AML1 gene rearrangement in a child with acute lymphoblastic leukemia.
|
11106815 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
ETV6/CBFA2 fusions in childhood B-cell precursor acute lymphoblastic leukemia with myeloid markers.
|
11129441 |
2000 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
AlteredExpression
|
disease |
BEFREE |
Chemosensitivity of TEL-AML1 fusion transcript positive acute lymphoblastic leukemia cells.
|
11378579 |
2001 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Relapse of TEL-AML1--positive acute lymphoblastic leukemia in childhood: a matched-pair analysis.
|
11432885 |
2001 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
The association of the TEL-AML1 chromosomal translocation with the accumulation of methotrexate polyglutamates in lymphoblasts and with ploidy in childhood B-progenitor cell acute lymphoblastic leukemia: a Pediatric Oncology Group study.
|
11455977 |
2001 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Novel cryptic, complex rearrangements involving ETV6-CBFA2 (TEL-AML1) genes identified by fluorescence in situ hybridization in pediatric patients with acute lymphoblastic leukemia.
|
11550288 |
2001 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia.
|
11579464 |
2001 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
GeneticVariation
|
disease |
BEFREE |
Expression of TEL-AML1 fusion transcripts and response to induction therapy in standard risk acute lymphoblastic leukemia.
|
11699220 |
2001 |
|
Precursor Cell Lymphoblastic Leukemia Lymphoma
|
0.400 |
Biomarker
|
disease |
BEFREE |
Fluorescence in situ hybridization study of TEL/AML1 fusion and other abnormalities involving TEL and AML1 genes. Correlation with cytogenetic findings and prognostic value in children with acute lymphocytic leukemia.
|
11726315 |
2001 |