RUNX1, RUNX family transcription factor 1, 861

N. diseases: 412; N. variants: 75
Disease: Esophageal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.120 Biomarker group BEFREE These results indicated that lincRNA-uc002yug.2 might involve in AS of RUNX1/AML1 and serve as a predictor for esophageal cancer and prognosis. 25486427 2015
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.120 AlteredExpression group BEFREE Amplified loci implicated genes with known involvement in carcinogenesis but also pointed to regions harboring potentially novel cancer genes, including a recurrent deletion found in 15% of esophageal tumors where the Runt transcription factor subunit RUNX1 was implicated, including by functional experiments in tissue culture. 22751462 2012
CUI: C0014859
Disease: Esophageal Neoplasms
Esophageal Neoplasms 		0.120 GeneticVariation group GWASCAT Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations. 21642993 2011