RUNX1, RUNX family transcription factor 1, 861

N. diseases: 412; N. variants: 75
Disease: Patau syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0152095
Disease: Patau syndrome
Patau syndrome 		0.020 GeneticVariation disease BEFREE In conclusion, our results show that trisomy 13 is correlated to RUNX1 mutation and increased FLT3 expression in AML-M0. 17650443 2007
CUI: C0152095
Disease: Patau syndrome
Patau syndrome 		0.020 GeneticVariation disease BEFREE Quantitation of FLT3 transcript levels revealed a highly significant (P < .001) about 5-fold increase in AML with RUNX1 mutations and trisomy 13 compared with samples without trisomy 13. 17485549 2007