|
Malignant neoplasm of breast
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
The results showed that the expression level of STC2 gene in 50 cases of breast cancer tissues was significantly higher than that in paracancer normal breast tissues (P<0.001).
|
31845230 |
2019 |
|
Malignant neoplasm of breast
|
0.350 |
Biomarker
|
disease |
BEFREE |
MDA-MB-231 and T47D cell lines were selected and separately introduced with miR-190 inhibitors, activators, and small interfering RNAs with the intent of exploring the regulatory functions that miR-190 has shown while governing STC2 in BC.
|
30993707 |
2019 |
|
Breast Carcinoma
|
0.350 |
Biomarker
|
disease |
BEFREE |
MDA-MB-231 and T47D cell lines were selected and separately introduced with miR-190 inhibitors, activators, and small interfering RNAs with the intent of exploring the regulatory functions that miR-190 has shown while governing STC2 in BC.
|
30993707 |
2019 |
|
Breast Carcinoma
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
The results showed that the expression level of STC2 gene in 50 cases of breast cancer tissues was significantly higher than that in paracancer normal breast tissues (P<0.001).
|
31845230 |
2019 |
|
Malignant neoplasm of breast
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
The association between IHC expression of STC1 and STC2 in primary breast tumor tissue microarrays and breast cancer recurrence was evaluated within median time to recurrence quintiles.<b>Results:</b> The association between STC1 expression, dichotomized as positive or negative, and recurrence was strongly positive for the final time quintile (6-10 years postdiagnosis) in the ER<sup>+</sup>/TAM<sup>+</sup> group [aOR = 2.70; 95% confidence interval (CI): 1.22-5.98].
|
29593009 |
2018 |
|
Breast Carcinoma
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
The association between IHC expression of STC1 and STC2 in primary breast tumor tissue microarrays and breast cancer recurrence was evaluated within median time to recurrence quintiles.<b>Results:</b> The association between STC1 expression, dichotomized as positive or negative, and recurrence was strongly positive for the final time quintile (6-10 years postdiagnosis) in the ER<sup>+</sup>/TAM<sup>+</sup> group [aOR = 2.70; 95% confidence interval (CI): 1.22-5.98].
|
29593009 |
2018 |
|
Malignant neoplasm of breast
|
0.350 |
Biomarker
|
disease |
CTD_human |
Constitutive STC2 expression in human breast cancer cell lines resulted in significant impairment of cell growth, migration and cell viability after serum withdrawal.
|
18492817 |
2008 |
|
Malignant neoplasm of breast
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
Constitutive STC2 expression in human breast cancer cell lines resulted in significant impairment of cell growth, migration and cell viability after serum withdrawal.
|
18492817 |
2008 |
|
Breast Carcinoma
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
Constitutive STC2 expression in human breast cancer cell lines resulted in significant impairment of cell growth, migration and cell viability after serum withdrawal.
|
18492817 |
2008 |
|
Breast Carcinoma
|
0.350 |
Biomarker
|
disease |
CTD_human |
Constitutive STC2 expression in human breast cancer cell lines resulted in significant impairment of cell growth, migration and cell viability after serum withdrawal.
|
18492817 |
2008 |
|
Malignant neoplasm of breast
|
0.350 |
Biomarker
|
disease |
BEFREE |
Stanniocalcin 2 is an estrogen-responsive gene coexpressed with the estrogen receptor in human breast cancer.
|
11888893 |
2002 |
|
Breast Carcinoma
|
0.350 |
AlteredExpression
|
disease |
BEFREE |
The expression profile of STC2 was further confirmed by in situ hybridization and immunohistochemistry on a larger cohort of 236 unselected breast carcinomas using tissue microarrays.
|
11888893 |
2002 |
|
Mammary Neoplasms
|
0.340 |
AlteredExpression
|
group |
BEFREE |
The association between IHC expression of STC1 and STC2 in primary breast tumor tissue microarrays and breast cancer recurrence was evaluated within median time to recurrence quintiles.<b>Results:</b> The association between STC1 expression, dichotomized as positive or negative, and recurrence was strongly positive for the final time quintile (6-10 years postdiagnosis) in the ER<sup>+</sup>/TAM<sup>+</sup> group [aOR = 2.70; 95% confidence interval (CI): 1.22-5.98].
|
29593009 |
2018 |
|
Mammary Neoplasms
|
0.340 |
Biomarker
|
group |
CTD_human |
Breast tumour gene profiling studies have demonstrated significantly upregulated STC2 expression in hormone-responsive positive breast tumours; therefore, the purpose of this study was to investigate STC2 hormonal regulation and function in breast cancer cells.
|
18492817 |
2008 |
|
Mammary Neoplasms
|
0.340 |
AlteredExpression
|
group |
LHGDN |
Tumor dormancy: elevated expression of stanniocalcins in late relapsing breast cancer.
|
18355956 |
2008 |
|
Mammary Neoplasms
|
0.340 |
AlteredExpression
|
group |
BEFREE |
Breast tumour gene profiling studies have demonstrated significantly upregulated STC2 expression in hormone-responsive positive breast tumours; therefore, the purpose of this study was to investigate STC2 hormonal regulation and function in breast cancer cells.
|
18492817 |
2008 |
|
Mammary Neoplasms
|
0.340 |
Biomarker
|
group |
LHGDN |
A tissue microarray containing 245 invasive breast tumors from women treated with curative surgery followed by anthracycline-based chemotherapy and hormone therapy for the estrogen receptor (ER)-positive tumors was screened by in situ hybridization with probes against thrombospondin 3 (TSP3), insulin-like growth factor binding protein 7 (IGFBP7), tumor rejection antigen 1 (TRA1), stanniocalcin 2 (STC2), and netrin 4 (NTN4).
|
17545519 |
2007 |
|
Non-alcoholic Fatty Liver Disease
|
0.300 |
Biomarker
|
disease |
CTD_human |
The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease.
|
24097666 |
2014 |
|
Nonalcoholic Steatohepatitis
|
0.300 |
Biomarker
|
disease |
CTD_human |
The adaptive endoplasmic reticulum stress response to lipotoxicity in progressive human nonalcoholic fatty liver disease.
|
24097666 |
2014 |
|
Endometriosis
|
0.300 |
Biomarker
|
disease |
CTD_human |
Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis.
|
20864642 |
2011 |
|
Endometrioma
|
0.300 |
Biomarker
|
disease |
CTD_human |
Unique transcriptome, pathways, and networks in the human endometrial fibroblast response to progesterone in endometriosis.
|
20864642 |
2011 |
|
Mammary Neoplasms, Human
|
0.300 |
Biomarker
|
disease |
CTD_human |
Stanniocalcin 2 expression is regulated by hormone signalling and negatively affects breast cancer cell viability in vitro.
|
18492817 |
2008 |
|
Mammary Carcinoma, Human
|
0.300 |
Biomarker
|
disease |
CTD_human |
Stanniocalcin 2 expression is regulated by hormone signalling and negatively affects breast cancer cell viability in vitro.
|
18492817 |
2008 |
|
Mammary Neoplasms, Experimental
|
0.200 |
Biomarker
|
phenotype |
RGD |
Differential gene signatures in rat mammary tumors induced by DMBA and those induced by fractionated gamma radiation.
|
18959458 |
2008 |
|
Reperfusion Injury
|
0.200 |
Biomarker
|
disease |
RGD |
Characterization of stanniocalcin 2, a novel target of the mammalian unfolded protein response with cytoprotective properties.
|
15485913 |
2004 |