Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.040 Biomarker disease BEFREE AML1-ETO driven acute leukemia: insights into pathogenesis and potential therapeutic approaches. 22875638 2012
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.040 Biomarker disease BEFREE Here we report that AML1-ETO collaborates with FLT3-LM in inducing acute leukemia in a murine BM transplantation model. 16025155 2005
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.040 AlteredExpression disease BEFREE Therefore, ETO is a bona fide corepressor that links the transcriptional pathogenesis of acute leukemias and B-cell lymphomas and offers a compelling target for transcriptional therapy of hematologic malignancies. 14551142 2004
CUI: C0085669
Disease: Acute leukemia
Acute leukemia
0.040 Biomarker disease BEFREE Animals reconstituted with AML1-ETO-expressing cells exhibited many of the hematopoietic developmental abnormalities seen in the bone marrow of human patients with the t(8;21), although the animals did not develop acute leukemia. 12732184 2004