UNC5C, unc-5 netrin receptor C, 8633

N. diseases: 47; N. variants: 10
Disease: Colorectal Neoplasms ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.040 AlteredExpression group BEFREE Expression of the netrin-1 dependence receptor UNC5C is reduced in many colorectal tumors; mice with the UNC5C mutations have increased progression of intestinal tumors. 21893118 2011
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.040 GeneticVariation group LHGDN Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer. 18054557 2007
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.040 AlteredExpression group LHGDN Inactivation of the UNC5C Netrin-1 receptor is associated with tumor progression in colorectal malignancies. 17967459 2007
CUI: C0009404
Disease: Colorectal Neoplasms
Colorectal Neoplasms 		0.040 GeneticVariation group BEFREE Moreover, sequencing of UNC5C gene in patients with colorectal tumors revealed the presence of missense mutations. 12655055 2003