RUNX3, RUNX family transcription factor 3, 864

N. diseases: 281; N. variants: 16
Disease: Chronic gastritis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085695
Disease: Chronic gastritis
Chronic gastritis 		0.010 PosttranslationalModification disease BEFREE The RUNX3 methylation was found in 8.1% of chronic gastritis (n=99), 28.1% of intestinal metaplasia (n=32), 27.3% of gastric adenomas (n=77) and 64% of gastric carcinomas (n=75), but not in chronic hepatitis B, normal prostate and colon mucosa, even though in cases of chronic hepatitis, the methylation frequency of its neoplastic tissues was very high. 14968123 2004