RUNX3, RUNX family transcription factor 3, 864

N. diseases: 281; N. variants: 16
Disease: Aplasia Cutis Congenita ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0282160
Disease: Aplasia Cutis Congenita
Aplasia Cutis Congenita 		0.040 AlteredExpression disease BEFREE Meanwhile, we measured the levels of Pim-1 and RUNX3 in the ACC tissues. 25551195 2014
CUI: C0282160
Disease: Aplasia Cutis Congenita
Aplasia Cutis Congenita 		0.040 PosttranslationalModification disease BEFREE Our findings indicate that RUNX3 methylation may occur as a common event in the development of ACC and that methylation may be a major mechanism for inactivation of RUNX3 in ACC. 21567090 2011
CUI: C0282160
Disease: Aplasia Cutis Congenita
Aplasia Cutis Congenita 		0.040 AlteredExpression disease BEFREE Our results suggest that low expression or deletion of RUNX3 in salivary gland tumors might play a pivotal role in tumorigenesis and tumor progression and poor prognosis in the case of salivary gland ACC and MEC. 21105967 2011
CUI: C0282160
Disease: Aplasia Cutis Congenita
Aplasia Cutis Congenita 		0.040 AlteredExpression disease BEFREE Our results demonstrate the expression of RUNX3 in normal salivary glands and salivary ACCs. 18410404 2008