SOCS1, suppressor of cytokine signaling 1, 8651

N. diseases: 315; N. variants: 7
Disease: Periodontal Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031090
Disease: Periodontal Diseases
Periodontal Diseases 		0.020 PosttranslationalModification group BEFREE SOCS1 gene promoter methylation, with its potential effects on the expression of this gene, seems to be a consequence of exposure to tobacco and not to periodontal disease. 31169909 2019
CUI: C0031090
Disease: Periodontal Diseases
Periodontal Diseases 		0.020 Biomarker group BEFREE Gingival tissues affected by experimental periodontitis express SOCS1, indicating that this protein may potentially downregulate signaling events involved in inflammatory reactions and bone loss and thus may play a relevant role in the development and progression of periodontal disease. 29019549 2017