SOCS1, suppressor of cytokine signaling 1, 8651

N. diseases: 315; N. variants: 7
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 Biomarker disease BEFREE Sepsis led to an elevation of miR-30a and also a decline of SOCS-1 in the liver cells. 30972748 2019
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 Biomarker disease BEFREE In summary, treatment of mice with SOCS1-silenced DCs can protect mice from systemic infection during the early stages and thereby increase overall survival. 29581081 2018
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 Biomarker disease BEFREE These results reveal a role of SOCS1 as a regulator of metabolic reprograming that prevents overwhelming inflammatory response and organ damage during sepsis. 28679957 2017
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 Biomarker disease RGD Sepsis-induced muscle growth hormone resistance occurs independently of STAT5 phosphorylation. 12644450 2003
CUI: C0243026
Disease: Sepsis
Sepsis
0.230 Biomarker disease RGD Differential expression of suppressors of cytokine signalling genes in response to nutrition and growth hormone in the septic rat. 11312157 2001