DYNLL1, dynein light chain LC8-type 1, 8655

N. diseases: 103; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 AlteredExpression phenotype BEFREE Aberrant DLC-1 expression may play an important role in cancer genesis and metastasis. 26514520 2015
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 AlteredExpression phenotype BEFREE Detecting the changes of the expression of DLC-1 in the breast carcinoma may contribute to earlier auxiliary diagnosis of invasiveness, metastasis and recrudescence. 22799310 2012
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE Nuclear overexpression of MYC protein occurred frequently in luminal cells of PIN, as well as in most primary carcinomas and metastatic disease. 18567993 2008
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.040 Biomarker phenotype BEFREE The RhoGAP protein DLC-1 functions as a metastasis suppressor in breast cancer cells. 16024604 2005