HYAL2, hyaluronidase 2, 8692

N. diseases: 54; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 Biomarker phenotype BEFREE The suppressive role of HYAL1 and HYAL2 in the metastasis of colorectal cancer. 30972813 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 GeneticVariation phenotype BEFREE In addition, high expression levels of both S100P and HYAL2 showed significant association with different clinicopathological characteristics, such as more recurrence events (P=0.004), and higher occurrence of metastasis (P=0.002). 26112095 2015
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.030 AlteredExpression phenotype BEFREE HYAL1 mRNA was absent in all specimens, whereas HYAL2 was expressed as two splice variants, of which HYAL2-var2 was overexpressed in solid metastases compared to effusions and primary carcinomas (p < 0.001). 23202930 2012